The contract is for the construction of a general hospital in the city of Tapachula, in the country's southern Chiapas state.
If the operation succeeds it would create a company with Ebitda of 6.6bn euros and operations in 15 countries.
The last stage of the Belgrano Cargas rehabilitation entails the renovation of 558km of rail lines across four provinces, and the recovery of a stretch that has been inactive for 20 years.
The bill proposes the creation of a water authority in charge of managing the country's water resources.
The US$140mn initiative entails the rehabilitation and paving of more than 96km of roads, including access corridors and urban crossings.
The investment, an initiative under the so-called Alliance for Prosperity plan, will include public and private funds, as well as US$750mn in financing from the IDB.
Chinese companies have in recent years shown increasing interest in investing in Panama's infrastructure sector.